About Cayuse Human Ethics
is UCA’s official platform for all IRB protocol submissions. All faculty, staff, and students conducting research with human participants use this system to submit, track, and manage their protocols from start to finish.
Online from Start to Finish
Submit, track, and manage your IRB protocols entirely online with real-time status updates. No more email chains or lost attachments.
CITI Training Integration
Cayuse HE integrates directly with CITI to automatically verify your training compliance status, eliminating the need to manually upload certificates.
Connected to Sponsored Projects
Integration with Cayuse Sponsored Projects connects your IRB approvals directly to your grant applications and awards, reducing duplicate data entry.
Smarter Submissions
The intelligent questionnaire guides you through only the questions relevant to your specific research, reducing errors and delays in the review process.
Getting Started
Faculty accounts are set up automatically. Students must request access before submitting.
Students: Request Access First
Before submitting, students must request system access using the . Legacy PDF+Email submissions are not accepted from students.
📄 UCA IRB Application Worksheet
Not sure what to expect before you start? Download the UCA IRB Application Worksheet 鈥� a PDF mockup of the full Cayuse HE application that lets you review all the questions and gather your information before logging in to submit.
Before You Submit
- Update your All researchers must complete the “Research Investigators (Students, faculty, staff)” course for every level of review. External funding or research beyond human ethics may require additional courses.
- Prepare your documents. Gather consent forms, letters of permission from external facilities, recruitment materials, surveys, interview protocols, and any other data collection materials before starting your application.
- Plan your timing. The system saves automatically, but having all materials ready before you begin will make the process much smoother.
Need a walkthrough? The takes you through the process step by step. Org Approvers can find their own walkthrough .
Submitting a New Protocol
All new IRB protocols should be submitted through . Legacy PDF+Email submissions are only accepted in limited circumstances and will add 1-2 weeks to your review timeline due to manual entry requirements.
Required: Cayuse HE for These Submissions
- Students: All submissions must go through Cayuse HE. Legacy PDF+Email submissions will not be accepted.
- Exempt applications (all researchers): Must be submitted through Cayuse HE. Legacy submissions will not be accepted.
Modifications to Existing Studies
How you submit a modification depends on your study type:
- Full Board studies: Already in Cayuse HE. Submit modifications using your existing study shell.
- Expedited and Exempt studies: Submit as a new study in Cayuse HE. Add “(Legacy IRB #00-000)” to your title, include both IRB numbers on all documents, and attach a description of the modifications and their rationale. Continue current activities while under review, but wait for approval before implementing changes.
Continuing Reviews (Full Board Studies Only)
- Full board applications from the last three years are in Cayuse HE as shells.
- Copy your existing information into the shell in Cayuse HE; no new content is needed.
- Submit one month before your expiration date.
- Modifications cannot be bundled with continuing reviews. Submit them separately and be mindful of full board deadlines.
Final Reports
If a final report is your only remaining action, you may use the legacy PDF+Email process. No Cayuse HE action is required for final reports only. Remember to download the PDF before completing your study record.
Training & Support
The Research Compliance Office offers several ways to get help with Cayuse HE:
Drop-In Sessions
Virtual (Zoom) and in-person drop-in sessions are available for an overview of the system, Q&A, and help with specific submission questions. Bring your questions!
Targeted Department Training
Need something more tailored? The RCO is happy to bring training directly to your department, lab, or research team. Reach out to schedule a session focused on your unit’s needs.
Submission Walkthrough Guides
Step-by-step guides are available for and for .
Questions? We’re here to help.
Contact Lasi McGhee, UCA Research Compliance Officer, at researchcompliance@uca.edu.
Access the system at .